Hypothesis test
Randomized Controlled Trial (RCT)
A randomized controlled trial (RCT) is the gold standard experimental design in clinical and health research, in which participants are randomly allocated to a treatment group or a control group so that the effect of an intervention can be measured with the highest possible degree of internal validity. The modern parallel-group RCT was formalized by Austin Bradford Hill and the Medical Research Council in their landmark streptomycin trial of 1948, and its reporting is governed today by the CONSORT 2010 guidelines (Schulz et al., 2010).
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Sources
- Schulz, K.F., Altman, D.G., Moher, D., for the CONSORT Group (2010). CONSORT 2010 Statement: Updated Guidelines for Reporting Parallel Group Randomised Trials. BMJ, 340, c332. DOI: 10.1136/bmj.c332 ↗
- Pocock, S.J. (1983). Clinical Trials: A Practical Approach. Wiley. ISBN: 978-0471901853
Related methods
Referenced by
A/B TestAdaptive A/B testAdaptive Clinical Trial DesignAdaptive Control Group Experimental DesignAdaptive ExperimentAdaptive Field ExperimentAdaptive Pretest-Posttest Experimental DesignAdaptive Randomized Controlled TrialAdaptive Solomon Four-Group DesignAdaptive Trial DesignBlocked A/B TestBlocked Laboratory ExperimentBlocked Pretest-Posttest Experimental DesignBlocked Randomized Controlled TrialBlocked Solomon Four-Group DesignCluster Randomized Control Group Experimental DesignCluster Randomized Controlled TrialCluster Randomized Field ExperimentCluster Randomized Laboratory ExperimentCluster Randomized Multiple Baseline DesignCluster Randomized TrialConjoint AnalysisControl Group Experimental DesignCrossover ABAB DesignCrossover Randomized Controlled TrialCrossover Single-Subject Experimental DesignDiagnostic Accuracy Study DesignDouble-blind A/B testDouble-blind adaptive experimentDouble-blind Control Group Experimental DesignDouble-blind field experimentDouble-blind laboratory experimentDouble-blind pretest-posttest experimental designDouble-blind Solomon four-group designEquivalence / Non-Inferiority TrialEvaluation-focused Intervention Mixed MethodsFactorial Control Group Experimental DesignFactorial ExperimentFactorial Field ExperimentFactorial Laboratory ExperimentFactorial Randomized Controlled TrialField ExperimentFractional Factorial ExperimentFull Factorial ExperimentIntervention Mixed Methods DesignLaboratory ExperimentMatched Phase III Clinical TrialMeta-analytic Phase II clinical trialMeta-analytic Phase III Clinical TrialMeta-analytic Phase IV StudyMeta-analytic Randomized Clinical TrialMulti-arm experimentMulti-Armed BanditN-of-1 TrialNatural ExperimentPilot Control Group Experimental DesignPilot Factorial ExperimentPilot Field ExperimentPilot Multi-Arm ExperimentPilot pretest-posttest experimental designPilot Randomized Controlled TrialPilot Solomon Four-Group DesignPragmatic A/B TestPragmatic adaptive experimentPragmatic Clinical TrialPragmatic Factorial ExperimentPragmatic Field ExperimentPragmatic Fractional Factorial ExperimentPragmatic Laboratory ExperimentPragmatic Multiple Baseline DesignPragmatic phase III clinical trialPragmatic Randomized Controlled TrialPretest-Posttest Experimental DesignQuantitative-dominant intervention mixed methodsRisk-adjusted cohort studySequential DesignSimulation-assisted confirmatory researchSingle-blind A/B testSingle-blind control group experimental designSingle-blind Factorial ExperimentSingle-blind multi-arm experimentSingle-blind pretest-posttest experimental designSingle-blind Randomized Controlled TrialSolomon Four-Group Design