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Single-blind Multi-arm Experiment

A single-blind multi-arm experiment is a controlled experimental design that simultaneously compares three or more treatment conditions while blinding participants — but not investigators — to their group assignment. This configuration reduces response bias driven by participants' expectations, preserves operational feasibility when full blinding is impractical, and allows direct pairwise and omnibus comparisons across multiple arms within a single study.

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Sources

  1. Friedman, L. M., Furberg, C. D., & DeMets, D. L. (2010). Fundamentals of Clinical Trials (4th ed.). Springer. ISBN: 978-1441915849
  2. Multi-arm clinical trial. Wikipedia. link

Related methods

ScholarGateSingle-blind multi-arm experiment (Single-blind Multi-arm Experimental Design). Retrieved 2026-06-04 from https://scholargate.app/en/experimental-design/single-blind-multi-arm-experiment