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嵌套病例对照研究

嵌套病例对照研究是一种嵌入在已定义队列中的高效观察性设计。对于每个出现研究兴趣结局(病例)的参与者,都会从当时仍处于风险中的个体中抽取少量匹配的对照。这种密度抽样策略产生的优势比(odds ratio)近似于来自完整队列的发生率比(incidence-rate ratio),而数据收集成本仅为其一小部分——当为所有队列成员测量暴露成本过高或技术要求过高时,它便成为首选替代方案。

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来源

  1. Thomas, D. C. (1977). Addendum to: Methods of cohort analysis: Appraisal by application to asbestos mining. Journal of the Royal Statistical Society, Series A, 140(4), 469–491. link
  2. Mantel, N. (1973). Synthetic retrospective studies and related topics. Biometrics, 29(3), 479–486. DOI: 10.2307/2529171

如何引用本页

ScholarGate. (2026, June 3). Nested Case-Control Study. ScholarGate. https://scholargate.app/zh/epidemiology/nested-case-control

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被引用于

ScholarGateNested case-control (Nested Case-Control Study). 于 2026-06-15 检索自 https://scholargate.app/zh/epidemiology/nested-case-control · 数据集: https://doi.org/10.5281/zenodo.20539026