Process / pipelineClinical / epidemiology
匹配的嵌套病例对照研究
匹配的嵌套病例对照研究是一种嵌入在已定义队列中的高效观察性设计。当一名参与者出现目标结局（病例）时，会从当时仍处于风险中的个体中抽取少量对照，并根据年龄、性别或时间等关键变量与病例进行匹配。这种设计保留了底层队列的时间结构，同时显著降低了暴露测量的成本。
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来源
- Rothman, K.J., Greenland, S., & Lash, T.L. (2008). Modern Epidemiology (3rd ed.). Lippincott Williams & Wilkins. ISBN: 978-0781755641
- Thomas, D.B. (1977). Methodology for assessing interaction in epidemiological studies of matched pairs. Biometrics, 33(3), 463-470. link ↗
如何引用本页
ScholarGate. (2026, June 3). Matched Nested Case-Control Study. ScholarGate. https://scholargate.app/zh/epidemiology/matched-nested-case-control
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