Process / pipelineBioinformatics / omics
教育研究中的全基因组关联研究
全基因组关联研究（GWAS）应用于教育研究，通过扫描人类基因组中的数百万个单核苷酸多态性（SNP），以识别与教育成果（如受教育年限、学位获得或认知测试分数）在统计学上显著相关的遗传变异。大型联盟——最著名的是社会科学基因关联联盟——已在数十万至数百万人中进行了里程碑式的研究，将GWAS确立为理解教育表型遗传结构的主要基因组学工具。
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来源
- Okbay, A., Turley, P., Georgios, K., et al. (2022). Polygenic prediction of educational attainment within and between families from genome-wide association analyses in 3 million individuals. Nature Genetics, 54(4), 437–449. link ↗
- Lee, J. J., Wedow, R., Okbay, A., et al. (2018). Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals. Nature Genetics, 50(8), 1112–1121. link ↗
如何引用本页
ScholarGate. (2026, June 3). Genome-Wide Association Study Applied to Educational Outcomes. ScholarGate. https://scholargate.app/zh/bioinformatics/gwas-in-educational-research
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Bayesian genome-wide association study in educational researchEpigenome-wide association study in educational researchGenome-wide association studyBayesian epigenome-wide association study in educational researchMachine learning-assisted genome-wide association studyPolygenic Risk ScoreSingle-cell GWASNetwork-based GWAS