Process / pipelinePopulation genetics
F统计量 (FST)
F统计量是一系列由Sewall Wright开发的度量方法，用于量化群体遗传结构以及群体间遗传分化的程度。FST是最广泛使用的F统计量，它衡量了归因于群体间差异而非群体内差异的总遗传变异的比例。FST的取值范围从零（无分化）到一（完全分化）。这些统计量已成为理解群体结构、检测群体混合以及分析塑造遗传变异的进化力量的基本工具。
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来源
- Wright, S. (1951). The genetical structure of populations. Annals of Eugenics, 15(4), 323–354. DOI: 10.1111/j.1469-1809.1949.tb02451.x ↗
- Weir, B. S., & Cockerham, C. C. (1984). Estimating F-statistics for the analysis of population structure. Evolution, 38(6), 1358–1370. DOI: 10.1111/j.1558-5646.1984.tb05657.x ↗
- Hudson, R. R., Boos, D. D., & Kaplan, N. L. (1992). A statistical test for detecting geographic subdivision in nucleotide sequences. Molecular Biology and Evolution, 9(3), 405–418. link ↗
如何引用本页
ScholarGate. (2026, June 3). F-statistics for Population Differentiation and Genetic Structure. ScholarGate. https://scholargate.app/zh/genetics/f-statistics
Which method?
Set this method beside its closest kin and read them side by side — the library lays the books on the table; the choice is yours.
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