Process / pipelineDiffusion imaging
DTI Tractography
Diffusion Tensor Imaging Tractography (DTI tractography) is a non-invasive neuroimaging technique that maps white matter fiber bundles in the brain by tracking the three-dimensional diffusion of water molecules along axons. Pioneered by Basser, Mori, and Conturo in the 1990s, DTI tractography reveals the structural connectivity of the brain, enabling visualization of major pathways (corpus callosum, arcuate fasciculus, corticospinal tract) and assessment of fiber integrity. It is widely used in neurosurgical planning, neurological disease assessment, and brain connectivity research.
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Sources
- Basser, P. J., Mattiello, J., LeBihan, D. (1994). Estimation of the effective self-diffusion tensor from the NMR spin echo. Journal of Magnetic Resonance, Series B, 103(3), 247-254. DOI: 10.1006/jmrb.1994.1037 ↗
- Mori, S., Crain, B. J., Chacko, V. P., van Zijl, P. C. (1999). Three-dimensional tracking of axonal projections in the brain by magnetic resonance imaging. Annals of Neurology, 45(2), 265-269. DOI: 10.1002/1531-8249(199902)45:2<265::AID-ANA21>3.0.CO;2-3 ↗
- Conturo, T. E., Lori, N. F., Cull, T. S., et al. (1999). Tracking neuronal fiber pathways in the living human brain. Proceedings of the National Academy of Sciences, 96(18), 10422-10427. DOI: 10.1073/pnas.96.18.10422 ↗