Process / pipelineNon-invasive imaging
OCT Angiography
Optical Coherence Tomography Angiography (OCTA) is a non-invasive imaging technique that visualizes the microvasculature in the retina and choroid by detecting motion contrast from flowing blood. Developed by Jia and colleagues in 2012, OCTA uses repeated OCT scans of the same tissue location to identify blood flow based on the decorrelation signal. It has become a critical diagnostic tool in ophthalmology for detecting retinal and macular diseases without requiring fluorescein injection.
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Sources
- Jia, Y., Tan, O., Tokayer, J., et al. (2012). Split-spectrum amplitude-decorrelation angiography with optical coherence tomography. Optics Express, 20(4), 4710-4725. DOI: 10.1364/OE.20.004710 ↗
- Wang, R. K., An, L. (2012). Doppler optical micro-angiography for volumetric imaging of vascular perfusion in vivo. Optics Express, 14(17), 7881-7895. DOI: 10.1364/OE.14.007881 ↗
- Spaide, R. F., Fujimoto, J. G., Waheed, N. K. (2015). Image artifacts in optical coherence tomography angiography. Retina, 35(11), 2163-2180. DOI: 10.1097/IAE.0000000000000765 ↗