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ChIP-seq Peak Calling — 染色质免疫沉淀测序峰值检测

ChIP-seq峰值检测是一个计算流程，它基于染色质免疫沉淀实验的测序读数，识别出目标蛋白（如转录因子或组蛋白修饰）富集的基因组区域。它将原始测序数据转化为一组高置信度的全基因组结合位点或修饰位点，从而能够对基因调控、染色质状态和表观遗传机制进行下游分析。

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ChIP-seq Peak Calling
ATAC-seq 分析表观基因组关联研究 (EWAS)RNA-seq差异表达序列比对Single-cell RNA-seq anal…变异检测贝叶斯ChIP-seq峰识别差异ChIP-seq峰值识别差异性表观基因组关联研究机器学习辅助的ChIP-seq峰值识别

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来源

  1. Zhang, Y., Liu, T., Meyer, C. A., Eeckhoute, J., Johnson, D. S., Bernstein, B. E., Nusbaum, C., Myers, R. M., Brown, M., Li, W., & Liu, X. S. (2008). Model-based analysis of ChIP-seq (MACS). Genome Biology, 9(9), R137. DOI: 10.1186/gb-2008-9-9-r137 ↗
  2. Landt, S. G., Marinov, G. K., Kundaje, A., Kheradpour, P., Pauli, F., Batzoglou, S., Bernstein, B. E., Bickel, P., Brown, J. B., Cayting, P., Chen, Y., DeSalvo, G., Epstein, C., Fisher-Aylor, K. I., Euskirchen, G., Gerstein, M., Gertz, J., Hartemink, A. J., Hoffman, M. M., ... Snyder, M. (2012). ChIP-seq guidelines and practices of the ENCODE and modENCODE consortia. Genome Research, 22(9), 1813–1831. DOI: 10.1101/gr.136184.111 ↗

如何引用本页

ScholarGate. (2026, June 3). Chromatin Immunoprecipitation Sequencing Peak Calling. ScholarGate. https://scholargate.app/zh/bioinformatics/chip-seq-peak-calling

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被引用于

贝叶斯ChIP-seq峰识别差异ChIP-seq峰值识别差异性表观基因组关联研究表观基因组关联研究 (EWAS)机器学习辅助的ChIP-seq峰值识别多组学单细胞RNA测序分析RNA-seq差异表达序列比对单细胞ChIP-seq峰值调用时间序列ChIP-seq峰值调用

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ScholarGate — ChIP-seq Peak Calling (Chromatin Immunoprecipitation Sequencing Peak Calling). 于 2026-06-15 检索自 https://scholargate.app/zh/bioinformatics/chip-seq-peak-calling · 数据集： https://doi.org/10.5281/zenodo.20539026