Process / pipelinePituitary hormone deficiency quality of life
AGHDA: Adult Growth Hormone Deficiency Assessment
The AGHDA is a 25-item disease-specific quality of life questionnaire designed to assess the burden of adult growth hormone (GH) deficiency. Developed by Hunt, Werther, and colleagues in 2000, it evaluates symptoms and functional impairments directly related to GH deficiency, including fatigue, reduced muscle strength, weight gain, and psychological difficulties. The instrument is widely used in endocrinology practice and clinical trials to quantify the impact of GH replacement therapy.
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Sources
- Hunt, A. E., Werther, G. A., & Wrightson, P. (2000). The utility of AGHDA in identifying GH-deficient adults. Clin Endocrinol (Oxf), 52(3), 341-346. DOI: 10.1046/j.1365-2265.2000.00944.x ↗
- Abs, R., Feldt-Rasmussen, U., Mattsson, A. F., et al. (1999). Assessment of GH status in adults with childhood-onset GH deficiency. Clin Endocrinol (Oxf), 50(4), 457-463. DOI: 10.1046/j.1365-2265.1999.00685.x ↗