Process / pipelineVoxel-wise morphological analysis
Voxel-Based Morphometry
Voxel-Based Morphometry (VBM) is a whole-brain statistical technique for detecting local differences in gray matter volume or concentration from structural MRI. Introduced by John Ashburner and Karl Friston in 2000, VBM enables researchers to identify regional brain volume changes associated with disease, aging, learning, and other factors without requiring a priori region-of-interest definitions.
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Sources
- Ashburner, J., & Friston, K. J. (2000). Voxel-based morphometry—the methods. NeuroImage, 11(6), 805–821. DOI: 10.1006/nimg.2000.0582 ↗
- Good, C. D., Johnsrude, I. S., Ashburner, J., et al. (2001). A voxel-based morphometric study of ageing in 465 normal adult human brains. NeuroImage, 14(1), 21–36. DOI: 10.1006/nimg.2001.0786 ↗