Benjamini-Hochberg Procedure (FDR Control)

The Benjamini-Hochberg (BH) procedure, introduced by Yoav Benjamini and Yosef Hochberg in 1995, controls the false discovery rate (FDR) — the expected proportion of false positives among all rejected hypotheses — rather than the probability of any false positive. By tolerating a controlled fraction of false discoveries, it delivers far greater power than family-wise error rate methods such as Bonferroni or Holm, which is why it has become the standard tool for large-scale simultaneous testing in genomics, neuroimaging, and other high-throughput fields.