Analiza CRISPR skrininga
Analiza CRISPR skrininga obrađuje podatke iz grupnih genetičkih skrininga korišćenjem CRISPR-Cas9 sistema radi identifikacije gena neophodnih za rast ćelija, preživljavanje ili fenotip u specifičnim uslovima. Razvijen od strane Zhanga, Sanjane i saradnika, ovaj računarski postupak transformiše sekvencirane podatke o obilju vodećih RNK u rangirane liste funkcionalnih gena.
Pročitajte celu metodu
Prijavite se besplatnim nalogom da biste pročitali ovaj odeljak.
Method map
The neighbourhood of related methods — select a node to explore.
Izvori
- Shalem, O., Sanjana, N. E., Hartenian, E., Shi, X., Scott, D. A., Mikkelsen, T. S., ... & Zhang, F. (2014). Genome-scale CRISPR-Cas9 knockout screening in human cells. Science, 343(6166), 84-87. DOI: 10.1126/science.1247005 ↗
- Hart, T., Chandrashekhar, M., Aregger, M., Steinhart, Z., Brown, K. R., MacLeod, G., ... & Moffat, J. (2015). High-resolution CRISPR screens reveal fitness genes and pathways. Molecular Systems Biology, 11(8), 820. link ↗
- King, J. B., Palmer, A. C., & Sorger, P. K. (2020). Application of a genetic algorithm designed for flexible objective optimization in pharmaceutical research and development. Cancer Research, 79(13 Supplement), 3435. link ↗
Kako citirati ovu stranicu
ScholarGate. (2026, June 3). CRISPR Screening Data Analysis and Hit Identification. ScholarGate. https://scholargate.app/sr/bioinformatics/crispr-screen-analysis
Which method?
Set this method beside its closest kin and read them side by side — the library lays the books on the table; the choice is yours.
- De Novo asembliranje transkriptomaBioinformatika↔ compare
- Pretraga HMMER profilaBioinformatika↔ compare
- Metagenomic BinningBioinformatika↔ compare
Citirana u
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