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Matched Randomized Clinical Trial/Evidence
Method evidence record

Matched Randomized Clinical Trial

A matched randomized clinical trial pairs participants (or clusters) on key baseline characteristics before randomization, then allocates one member of each pair to treatment and the other to control. This design combines the causal validity of randomization with the covariate balance of matching, increasing statistical efficiency and reducing confounding from known prognostic variables without sacrificing the internal validity of a controlled experiment.

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Source record

Citations copied verbatim from the method’s source record. No claim-level verification is inferred from them.

Matched Randomized Clinical Trial
Taxonomic method record · process-pipeline / epidemiology
  • Imai, K., King, G., & Nall, C. (2009). The essential role of pair matching in cluster-randomized experiments, with application to the Mexican universal health insurance evaluation. Statistical Science, 24(1), 29–53. · DOI 10.1214/08-STS274
  • Greevy, R., Lu, B., Silber, J. H., & Rosenbaum, P. R. (2004). Optimal multivariate matching before randomization. Biostatistics, 5(2), 263–275. · DOI 10.1093/biostatistics/5.2.263
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Curated claims

Claims persisted in the evidence ledger, each with its own assessment.

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Related methods

Generated from the method graph and shown as machine-suggested relations — no evidence claim is inferred.

Taxonomic bucketAdaptive Randomized Clinical Trialmachine-suggested · Relational suggestion, not evidence.Taxonomic bucketMatched case-control studymachine-suggested · Relational suggestion, not evidence.Taxonomic bucketMulticenter Randomized Clinical Trialmachine-suggested · Relational suggestion, not evidence.Taxonomic bucketPragmatic randomized clinical trialmachine-suggested · Relational suggestion, not evidence.Taxonomic bucketProspective Randomized Clinical Trialmachine-suggested · Relational suggestion, not evidence.Taxonomic bucketRandomized clinical trialmachine-suggested · Relational suggestion, not evidence.

Evidence status

Sources recorded, not reviewed

Bibliographic sources are present. Claim-level evidence review has not been performed.

Sources

2 recorded citations, copied from the method source record.

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