Process / pipelineClinical / epidemiology

Matched Case-Control Study

A matched case-control study is an observational epidemiological design in which each case (a person with the disease or outcome of interest) is paired with one or more controls (persons without the outcome) who share one or more characteristics — such as age, sex, or clinical setting — to control confounding. Exposure history is then compared between cases and their matched controls to estimate the odds ratio of the exposure-disease association.

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Sources

  1. Rothman, K. J., Greenland, S., & Lash, T. L. (2008). Modern Epidemiology (3rd ed.). Lippincott Williams & Wilkins. ISBN: 978-0781755474
  2. Schlesselman, J. J. (1982). Case-Control Studies: Design, Conduct, Analysis. Oxford University Press. ISBN: 978-0195029338

Related methods

Referenced by

ScholarGateMatched case-control study (Matched Case-Control Study). Retrieved 2026-06-04 from https://scholargate.app/en/epidemiology/matched-case-control-study