Process / pipelineChromatographic Separation

Ion Chromatography

Ion chromatography is a liquid chromatography method that separates ions and polar molecules based on their relative affinity for the ion exchange resin in the column. Developed by Hamish Small in 1975, it combines ion-exchange separation with conductivity detection, enabling rapid, sensitive, and simultaneous determination of multiple ions in a single analysis. Ion chromatography has become an indispensable tool for monitoring environmental pollutants, analyzing food and pharmaceutical products, and studying complex ionic mixtures.

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Sources

  1. Small, H., Stevens, T. S., & Bauman, W. C. (1989). Novel ion exchange chromatographic method using conductometric detection. Analytical Chemistry, 47(11), 1801–1809. DOI: 10.1021/ac60363a003
  2. Weiss, J. (2004). Handbook of Ion Chromatography (3rd ed.). Wiley-VCH. ISBN: 978-3527289721
  3. Jackson, P. E., Haddad, P. R., & Alexander, P. W. (1997). Advances in ion chromatography. Journal of Chromatography A, 789(1-2), 17–33. DOI: 10.1016/s0021-9673(97)00699-8

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Referenced by

ScholarGateIon Chromatography (Ion Chromatography). Retrieved 2026-06-04 from https://scholargate.app/en/analytical-chemistry/ion-chromatography