Process / pipelinePatient-reported outcome
锚定最小重要性差异法
锚定最小重要性差异（Minimal Clinically Important Difference, MCID）法是一种确定患者报告结局（patient-reported outcome, PRO）中患者或临床医生认为有意义或重要的最小变化的技法。该方法由 Guyatt、Jaeschke 和 Singer 于 1989 年开创，它将结局评分的变化与外部具有临床意义的事件或判断联系起来，使研究人员和临床医生能够判断治疗效果是否代表了真实、与患者相关的改善。
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来源
- Jaeschke, R., Singer, J., & Guyatt, G. H. (1989). Measurement of health status: Ascertaining the minimal clinically important difference. Controlled Clinical Trials, 10(4), 407-415. DOI: 10.1016/0197-2456(89)90005-6 ↗
- Revicki, D., Hays, R. D., Cella, D., & Sloan, J. (2008). Recommended methods for determining responsiveness and minimally important differences for patient-reported outcomes. Journal of Clinical Epidemiology, 61(2), 102-109. DOI: 10.1016/j.jclinepi.2007.03.012 ↗
- Copay, A. G., Chung, A. S., Pfeiffer, T., Borframes, R., Braswell, K., Chou, L. C., & Spangehl, M. J. (2007). Minimum clinically important difference: a review of nomenclature, methods, and applications in speech-language pathology. Journal of Medical Speech-Language Pathology, 15(4), xlii-xliii. link ↗
如何引用本页
ScholarGate. (2026, June 3). Anchor-Based Method for Establishing Minimal Important Difference (Minimal Clinically Important Difference) in Patient-Reported Outcomes. ScholarGate. https://scholargate.app/zh/psychometrics/anchor-based-minimal-important-difference
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