方法对比

	贝叶斯病例对照研究	匹配病例对照研究
领域	流行病学	流行病学
方法族	Process / pipeline	Process / pipeline
起源年份	1990s–2000s (systematic application); Bayesian inference foundations: Bayes/Laplace 18th–19th c.	1950s–1970s
提出者	Sander Greenland (Bayesian epidemiology formalization); earlier Bayesian logistic methods: Leonard (1972)	Brian MacMahon and others; systematised by Schlesselman (1982)
类型	Observational analytic study with Bayesian inference	Observational analytic design
开创性文献	Greenland, S. (2006). Bayesian perspectives for epidemiological research: I. Foundations and basic methods. International Journal of Epidemiology, 35(3), 765-775.	Rothman, K. J., Greenland, S., & Lash, T. L. (2008). Modern Epidemiology (3rd ed.). Lippincott Williams & Wilkins. ISBN: 978-0781755474
别名	Bayesian case-control design, Bayesian odds ratio estimation, Bayesian matched case-control, Bayesian logistic regression case-control	matched case-referent study, individually matched case-control, pair-matched case-control, matched case-control design
相关	6	5
摘要	A Bayesian case-control study applies Bayesian statistical inference to the classic case-control epidemiological design, formally combining prior knowledge about exposure-disease associations with observed case and control data to estimate posterior odds ratios and credible intervals. Rather than relying solely on observed data, the Bayesian framework allows investigators to incorporate external evidence — from prior studies, expert knowledge, or mechanistic understanding — into the analysis, yielding probability statements about effect sizes that are often more interpretable than classical p-values and confidence intervals.	A matched case-control study is an observational epidemiological design in which each case (a person with the disease or outcome of interest) is paired with one or more controls (persons without the outcome) who share one or more characteristics — such as age, sex, or clinical setting — to control confounding. Exposure history is then compared between cases and their matched controls to estimate the odds ratio of the exposure-disease association.