เปรียบเทียบวิธี

	การสังเคราะห์อภิมานเชิงคุณภาพ	การสังเคราะห์เชิงสัจนิยม	การวิเคราะห์แก่นสาระ
สาขาวิชา	การสังเคราะห์หลักฐาน	การสังเคราะห์หลักฐาน	การวิจัยเชิงคุณภาพ
ตระกูล	Process / pipeline	Process / pipeline	Process / pipeline
ปีกำเนิด	2007	2005	2006
ผู้ริเริ่ม	Sandelowski & Barroso (2007), Popularized by Thomas & Harden (2008)	Ray Pawson (2005)	Virginia Braun and Victoria Clarke
ประเภท	Framework	Framework	Method
แหล่งต้นตำรับ	Thomas, J., & Harden, A. (2008). Methods for the thematic synthesis of qualitative research in systematic reviews. BMC Medical Research Methodology, 8, 45.	Pawson, R., Greenhalgh, T., Harvey, G., & Walshe, K. (2005). Realist review—a new method of systematic review designed for complex policy and programme evaluation. Journal of Health Services Research & Policy, 10(S1), 21–35.	Braun, V., & Clarke, V. (2006). Using thematic analysis in psychology. Qualitative Research in Psychology, 3(2), 77–101.
ชื่อเรียกอื่น	Qualitative Evidence Synthesis, Thematic Synthesis, Metasynthesis, Qualitative Systematic Review	Realist Review, CMO Configuration, Mechanism-Based Synthesis	TA, Reflexive Thematic Analysis
ที่เกี่ยวข้อง	2	1	3
สรุป	Qualitative meta-synthesis is a systematic method for synthesizing findings from multiple qualitative research studies (interviews, focus groups, ethnographies) to develop integrated interpretations and theoretical insights. Formalized by Sandelowski and Barroso (2007) and popularized by Thomas and Harden (2008), qualitative meta-synthesis preserves the rich, contextual, interpretive nature of qualitative evidence while enabling broader conclusions across multiple studies. Unlike quantitative meta-analysis, which pools numbers, qualitative meta-synthesis synthesizes themes, meanings, and conceptual insights—answering questions like 'How do cancer patients experience treatment side effects?' or 'What factors shape patient engagement with preventive health programs?' across multiple studies.	Realist synthesis is a theory-driven, interpretive method for evidence synthesis developed by Ray Pawson (2005) that focuses on understanding HOW and WHY interventions work, rather than WHETHER they work. Grounded in realist philosophy, realist synthesis examines Context-Mechanism-Outcome (CMO) configurations: how specific contextual conditions activate mechanisms that produce outcomes. Unlike traditional systematic reviews, which typically answer 'Does intervention X reduce outcome Y?', realist synthesis asks 'Under what conditions, through what mechanisms, for which populations does X work?' This approach is particularly valuable for complex interventions (policies, programs, multi-component treatments) where effectiveness varies dramatically across contexts, and for understanding why interventions succeed in some settings but fail in others.	Thematic Analysis (TA) is a qualitative research methodology for identifying, analyzing, and reporting patterns (themes) in qualitative data. Developed systematically by Virginia Braun and Victoria Clarke (2006), TA is flexible and accessible, applicable across diverse theoretical frameworks and data types, making it one of the most widely used qualitative methods in psychology, health research, and social sciences.