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Kopīgā trausluma modelis (Shared Frailty Model) grupētiem izdzīvošanas datiem×Kopīgais modelis longitudināliem datiem un notikuma iestāšanās laikam×
NozareDzīvildzeDzīvildze
SaimeSurvival analysisSurvival analysis
Izcelsmes gads19792004
AutorsVaupel, J.W., Manton, K.G. & Stallard, E.Tsiatis, A.A. & Davidian, M.; Rizopoulos, D.
TipsRandom effects survival modelSemiparametric regression model
PirmavotsVaupel, J.W., Manton, K.G. & Stallard, E. (1979). The Impact of Heterogeneity in Individual Frailty on the Dynamics of Mortality. Demography, 16(3), 439–454. DOI ↗Rizopoulos, D. (2012). Joint Models for Longitudinal and Time-to-Event Data. CRC Press. DOI ↗
Citi nosaukumishared frailty model, random effects survival model, Frailty Modeli (Paylaşılan Kırılganlık)joint model, shared random effects model, longitudinal-survival joint model, Joint Model (Boylamsal + Sağkalım Birleşik Model)
Saistītās35
KopsavilkumsThe shared frailty model, introduced by Vaupel, Manton, and Stallard in 1979, extends standard survival regression by incorporating a random effect — the 'frailty' — that captures unobserved heterogeneity among subjects or clusters. When survival outcomes are measured on individuals who share a common environment (patients in the same hospital, members of the same family, animals in the same litter), a frailty term accounts for the within-cluster dependence that ordinary Cox regression ignores.The joint model for longitudinal and time-to-event data, formalised by Tsiatis and Davidian in 2004 and extended comprehensively by Rizopoulos in 2012, simultaneously estimates a mixed-effects model for repeatedly measured biomarkers and a survival model for the time to an event, linking the two processes through shared random effects. It resolves two major problems that simpler approaches cannot handle: informative dropout from longitudinal studies and the endogeneity of time-varying biomarkers used as covariates in a Cox model.
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ScholarGateSalīdzināt metodes: Frailty Model · Joint Model for Longitudinal and Survival Data. Izgūts 2026-06-18 no https://scholargate.app/lv/compare