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시뮬레이션 기반 검정력 분석 (몬테카를로 검정력)×순차 분석 (그룹 순차 설계)×
분야통계학통계학
계열Hypothesis testHypothesis test
기원 연도20111977
창시자Arnold et al. (2011); Green & MacLeod (2016) for mixed-model extensionP. C. O'Brien & T. R. Fleming; P. C. Pocock
유형Simulation-based (Monte Carlo)Sequential / adaptive hypothesis test
원전Arnold, B.F. et al. (2011). Simulation Methods to Estimate Design Power: An Overview for Applied Research. BMC Medical Research Methodology, 11, 94. DOI ↗O'Brien, P.C. & Fleming, T.R. (1979). A Multiple Testing Procedure for Clinical Trials. Biometrics, 35(3), 549–556. DOI ↗
별칭Monte Carlo power analysis, Monte Carlo simulation power, MC power, Simülasyon Tabanlı Güç Analizi (Monte Carlo Power)sequential testing, group sequential design, interim analysis, Sıralı Analiz (Sequential Testing / Group Sequential Design)
관련65
요약Simulation-based power analysis estimates the statistical power and required sample size of a study by repeating a full analysis pipeline thousands of times on artificially generated data. Because it relies on Monte Carlo simulation rather than closed-form equations, it is applicable to designs — mixed models, complex measurement structures, non-standard outcomes — where analytical power formulas do not exist. The approach was systematically described for applied research by Arnold et al. in 2011, and the mixed-model implementation via the SIMR package was formalised by Green and MacLeod in 2016.Sequential analysis is a framework for conducting hypothesis tests with pre-planned interim looks at accumulating data, allowing a study to stop early for efficacy or futility while controlling the overall Type I error rate. The group sequential approach was formalised by Pocock (1977) and O'Brien and Fleming (1979), and remains the standard for confirmatory clinical trials and rigorous A/B experiments.
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