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위험 조정 생존 분석×Cox 비례 위험 모형×
분야역학역학
계열Process / pipelineProcess / pipeline
기원 연도1972 (Cox regression); broader covariate-adjusted survival methods developed 1970s–1990s1972
창시자D. R. Cox (regression framework); extensions via Kaplan & Meier, Breslow, and othersSir David Roxbee Cox
유형Observational and experimental analytical methodSemi-parametric regression model
원전Cox, D. R. (1972). Regression models and life-tables. Journal of the Royal Statistical Society, Series B, 34(2), 187–220. link ↗Cox, D. R. (1972). Regression models and life-tables. Journal of the Royal Statistical Society: Series B (Methodological), 34(2), 187–202. DOI ↗
별칭covariate-adjusted survival analysis, adjusted time-to-event analysis, risk-stratified survival analysis, adjusted Kaplan-Meier / Cox analysisCox regression, Cox PH model, proportional hazards model, CPH
관련55
요약Risk-adjusted survival analysis estimates the time to an event of interest — such as death, relapse, or hospital readmission — while simultaneously accounting for baseline differences in patient characteristics (covariates). By incorporating confounders such as age, comorbidities, or disease severity, it produces hazard ratios, survival curves, and median survival estimates that are attributable to the factor of interest rather than to pre-existing risk differences between groups.The Cox proportional hazards model is a semi-parametric regression method that estimates the effect of one or more covariates on the hazard — the instantaneous rate of an event such as death, relapse, or failure — while making no assumption about the shape of the baseline hazard function. Introduced by David Cox in 1972, it is the dominant tool for multivariable survival analysis in clinical and epidemiological research.
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