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위험 조정 경쟁 위험 분석×Cox 비례 위험 모형×
분야역학역학
계열Process / pipelineProcess / pipeline
기원 연도1999 (subdistribution hazard model); cause-specific hazard framework earlier1972
창시자Jason Fine and Robert GraySir David Roxbee Cox
유형Regression model for time-to-event data with competing eventsSemi-parametric regression model
원전Fine, J. P., & Gray, R. J. (1999). A proportional hazards model for the subdistribution of a competing risk. Journal of the American Statistical Association, 94(446), 496–509. DOI ↗Cox, D. R. (1972). Regression models and life-tables. Journal of the Royal Statistical Society: Series B (Methodological), 34(2), 187–202. DOI ↗
별칭competing risks regression, subdistribution hazard model, cause-specific hazard analysis, Fine-Gray modelCox regression, Cox PH model, proportional hazards model, CPH
관련45
요약Risk-adjusted competing risks analysis extends classical survival analysis to settings where subjects can experience more than one type of terminal event, and where the occurrence of one event prevents the occurrence of another. By modelling cause-specific or subdistribution hazards while adjusting for measured confounders, the method yields unbiased estimates of the absolute probability — the cumulative incidence function — of each event type over time in the presence of competing events.The Cox proportional hazards model is a semi-parametric regression method that estimates the effect of one or more covariates on the hazard — the instantaneous rate of an event such as death, relapse, or failure — while making no assumption about the shape of the baseline hazard function. Introduced by David Cox in 1972, it is the dominant tool for multivariable survival analysis in clinical and epidemiological research.
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