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전향적 생존 분석×Cox 비례 위험 모형×
분야역학역학
계열Process / pipelineProcess / pipeline
기원 연도1958–1972 (foundational methods); prospective design emphasis formalized by 1980s1972
창시자Kaplan & Meier (estimator, 1958); Cox (proportional hazards model, 1972); prospective design formalised in modern clinical epidemiologySir David Roxbee Cox
유형Longitudinal observational or experimental study design with time-to-event analysisSemi-parametric regression model
원전Kleinbaum, D. G., & Klein, M. (2012). Survival Analysis: A Self-Learning Text (3rd ed.). Springer. ISBN: 978-1441966452Cox, D. R. (1972). Regression models and life-tables. Journal of the Royal Statistical Society: Series B (Methodological), 34(2), 187–202. DOI ↗
별칭prospective time-to-event analysis, prospective failure-time analysis, forward-looking survival study, prospective event-time studyCox regression, Cox PH model, proportional hazards model, CPH
관련55
요약Prospective survival analysis is a longitudinal study design in which participants are enrolled before the event of interest occurs, followed forward in time under standardised conditions, and analysed using survival-analytic methods to estimate the time until a defined clinical endpoint — such as death, disease recurrence, or treatment failure. Because data are collected prospectively, exposure and covariate information are recorded before outcomes are known, substantially reducing recall and selection bias relative to retrospective approaches.The Cox proportional hazards model is a semi-parametric regression method that estimates the effect of one or more covariates on the hazard — the instantaneous rate of an event such as death, relapse, or failure — while making no assumption about the shape of the baseline hazard function. Introduced by David Cox in 1972, it is the dominant tool for multivariable survival analysis in clinical and epidemiological research.
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