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생존 연구를 위한 검정력 분석×Cox 비례 위험 모형×
분야통계학역학
계열Hypothesis testProcess / pipeline
기원 연도19811972
창시자Sir David Roxbee Cox
유형Sample size determination for survival outcomesSemi-parametric regression model
원전Schoenfeld, D. A. (1981). The asymptotic properties of nonparametric tests for comparing survival distributions. Biometrika, 68(1), 316–319. DOI ↗Cox, D. R. (1972). Regression models and life-tables. Journal of the Royal Statistical Society: Series B (Methodological), 34(2), 187–202. DOI ↗
별칭log-rank power analysis, cox regression power analysis, survival power analysis, Sağkalım Analizi Güç AnaliziCox regression, Cox PH model, proportional hazards model, CPH
관련65
요약Power analysis for survival studies determines how many participants — and how many observed events — are required so that a log-rank test or Cox regression has a sufficient probability of detecting a clinically meaningful difference in survival between groups. The foundational formulas were derived by Schoenfeld (1981) and Lachin (1981) and remain the standard approach in clinical trial planning.The Cox proportional hazards model is a semi-parametric regression method that estimates the effect of one or more covariates on the hazard — the instantaneous rate of an event such as death, relapse, or failure — while making no assumption about the shape of the baseline hazard function. Introduced by David Cox in 1972, it is the dominant tool for multivariable survival analysis in clinical and epidemiological research.
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