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다중 상태 생존 모형×Kaplan-Meier 생존 추정량×
분야생존분석생존분석
계열Survival analysisSurvival analysis
기원 연도19781958
창시자Andersen, P.K. & Keiding, N. (foundational framework); popularised by Putter, Fiocco & Geskus (2007)Kaplan, E. L. & Meier, P.
유형Semi-parametric hazard modelNon-parametric survival estimator
원전Putter, H., Fiocco, M. & Geskus, R.B. (2007). Tutorial in Biostatistics: Competing Risks and Multi-State Models. Statistics in Medicine, 26(11), 2389–2430. DOI ↗Kaplan, E. L. & Meier, P. (1958). Nonparametric Estimation from Incomplete Observations. Journal of the American Statistical Association, 53(282), 457–481. DOI ↗
별칭illness-death model, multi-state transition model, Çok Durumlu Model (Multi-State / Illness-Death)product-limit estimator, km curve, kaplan-meier sağkalım analizi
관련42
요약The multi-state model is a generalised survival framework, formalised in the work of Andersen and Keiding and brought to wide biostatistical practice by Putter, Fiocco and Geskus (2007), that models individuals moving through multiple distinct health states — for example, healthy, ill and dead — over time. A separate hazard function is estimated for each possible transition, and transition probabilities are recovered via the product-integral of the cumulative transition intensities.The Kaplan-Meier estimator, introduced by Kaplan and Meier in 1958, is a non-parametric method that estimates the survival curve — the probability of remaining event-free over time — from right-censored time-to-event data. The log-rank test is the companion procedure used to compare survival curves between groups.
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