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Matched Cox Proportional Hazards×Matched Cohort Study×
분야역학역학
계열Process / pipelineProcess / pipeline
기원 연도1972 (Cox model); matched extension widely adopted 1970s–1980sMid-20th century; propensity-score variant 1983
창시자D. R. Cox (Cox model, 1972); stratification extension for matched designs by subsequent methodologists including D. C. ThomasEstablished practice; propensity-score matching formalized by Rosenbaum & Rubin (1983)
유형Semi-parametric survival regression for matched dataObservational analytic study design
원전Cox, D. R. (1972). Regression models and life-tables. Journal of the Royal Statistical Society: Series B (Methodological), 34(2), 187–202. DOI ↗Rothman, K. J., Greenland, S., & Lash, T. L. (2008). Modern Epidemiology (3rd ed.). Lippincott Williams & Wilkins. ISBN: 978-0781755641
별칭stratified Cox regression, conditional Cox model, matched survival analysis, Cox model for matched pairsmatched follow-up study, paired cohort study, propensity-matched cohort, matched prospective study
관련45
요약Matched Cox proportional hazards is a survival analysis method that extends the Cox regression model to appropriately handle data arising from matched study designs — matched cohorts or matched case-control studies with time-to-event outcomes. By stratifying the partial likelihood by matched set, the method eliminates confounding from matching factors without estimating their baseline hazard, yielding valid hazard ratio estimates that are free from matching-induced bias.A matched cohort study is an observational design in which each exposed participant is paired with one or more unexposed counterparts who share key characteristics — such as age, sex, or comorbidity status — before both groups are followed forward in time to compare incident outcomes. Matching controls for measured confounders at the design stage, reducing bias that would otherwise require statistical adjustment alone.
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