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동등성 검정 (TOST×독립 표본 t-검정×
분야통계학통계학
계열Hypothesis testHypothesis test
기원 연도19871908
창시자Donald J. SchuirmannStudent (W. S. Gosset)
유형Parametric equivalence testParametric mean comparison
원전Schuirmann, D.J. (1987). A Comparison of the Two One-Sided Tests Procedure and the Power Approach for Assessing the Equivalence of Average Bioavailability. Journal of Pharmacokinetics and Biopharmaceutics, 15(6), 657–680. DOI ↗Student (1908). The probable error of a mean. Biometrika, 6(1), 1–25. DOI ↗
별칭TOST, two one-sided tests, bioequivalence test, Eşdeğerlik Testi (TOST — Two One-Sided Tests)student t-test, two-sample t-test, unpaired t-test, bağımsız örneklem t-testi
관련54
요약The equivalence test using the Two One-Sided Tests (TOST) procedure is a parametric hypothesis test designed to demonstrate that the difference between two group means falls within a pre-specified equivalence region ±Δ. Introduced by Schuirmann (1987) in the context of pharmaceutical bioequivalence, TOST reverses the logic of classical null-hypothesis testing: instead of trying to detect a difference, it provides positive evidence of similarity.The independent samples t-test is a parametric hypothesis test that compares the means of two independent groups to decide whether they differ significantly. It builds on the t-distribution introduced by Student (W. S. Gosset) in 1908 and assumes the measured values are continuous, approximately normally distributed, and have equal variances.
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