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비용효과 분석 (CEA)×의료 경제학에서의 마르코프 연쇄 모형×
분야보건경제학보건경제학
계열Process / pipelineProcess / pipeline
기원 연도19841983
창시자Drummond & Stoddart (Health Economics Research Group, McMaster University)Beck & Pauker (medical decision analysis, Massachusetts General Hospital)
유형MethodMethod
원전Gold, M. R., Siegel, J. E., Russell, L. B., & Weinstein, M. C. (Eds.). (1996). Cost-Effectiveness in Health and Medicine. New York: Oxford University Press. link ↗Beck, J. R., & Pauker, S. G. (1983). The Markov Process in Medical Prognosis. Medical Decision Making, 3(4), 419-458. DOI ↗
별칭CEA, ICER, Incremental Cost-Effectiveness RatioMarkov model, state transition model, cohort simulation
관련55
요약Cost-effectiveness analysis compares the incremental cost per unit of health benefit gained by one intervention relative to a comparator (standard care or best alternative). Developed rigorously in the 1980s by Drummond, Stoddart, and colleagues, CEA is now the standard framework for technology appraisal globally. NICE, HAS, CADTH, and other health technology assessment bodies use CEA to decide which treatments warrant public funding and at what price.A Markov model is a decision-analytic tool that simulates disease progression through defined health states over time, calculating cumulative costs and quality-adjusted life years (QALYs) to enable cost-effectiveness analysis. Developed by Beck and Pauker in 1983, Markov models are now the standard framework for projecting long-term outcomes of health interventions, especially chronic diseases where patients transition between clinical states (treatment response, disease progression, remission, death). Used by health technology assessment bodies and pharmaceutical companies to predict intervention value beyond trial duration.
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