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| Pragmatični faktorski eksperiment s frakcijama× | Metodologija površinskog odziva (RSM)× | |
|---|---|---|
| Područje | Eksperimentalni dizajn | Eksperimentalni dizajn |
| Obitelj≠ | Process / pipeline | Hypothesis test |
| Godina nastanka≠ | Fractional factorial designs: 1940s–1950s; pragmatic application: 2000s–2010s | 1951 |
| Tvorac≠ | Building on Fisher (1935); pragmatic adaptation by Collins, Murphy & Strecher (2007) via MOST framework | George E. P. Box & K. B. Wilson |
| Vrsta≠ | Experimental design | Second-order polynomial response surface model |
| Temeljni izvor≠ | Collins, L. M., Murphy, S. A., & Strecher, V. (2007). The multiphase optimization strategy (MOST) and the sequential multiple assignment randomized trial (SMART): New methods for more potent eHealth interventions. American Journal of Preventive Medicine, 32(5S), S112–S118. DOI ↗ | Box, G. E. P. & Wilson, K. B. (1951). On the experimental attainment of optimum conditions. Journal of the Royal Statistical Society, Series B, 13(1), 1–45. link ↗ |
| Drugi nazivi≠ | pragmatic FFE, fractional factorial trial, pragmatic factorial design, FFD in pragmatic settings | RSM, Central Composite Design, Box-Behnken Design, CCD |
| Srodne≠ | 4 | 7 |
| Sažetak≠ | A pragmatic fractional factorial experiment applies fractional factorial design principles to real-world or clinical intervention research, enabling simultaneous evaluation of multiple intervention components in a resource-efficient fraction of the full factorial runs. Popularised through the Multiphase Optimization Strategy (MOST), it identifies which components of a multi-component intervention contribute meaningfully to outcomes before a confirmatory randomized trial is conducted. | Response Surface Methodology is a collection of statistical and mathematical techniques for building an empirical second-order polynomial model that relates a continuous response variable to two or more controllable input factors, and then locating the factor settings that optimize that response. The approach was introduced by George E. P. Box and K. B. Wilson in their landmark 1951 paper and has since become a cornerstone of process optimization across engineering, chemistry, food science, and pharmaceutics. |
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