Bayesian Design of Experiments — Bayesian Optimal Experimental Design

Bayesian design of experiments selects experimental runs by maximising a utility function — typically the expected information gain — computed over prior beliefs about model parameters. Unlike classical design, which optimizes algebraic criteria such as D-optimality under fixed assumptions, Bayesian DOE incorporates prior knowledge and uncertainty about the system, yielding designs that are optimal in expectation across all plausible parameter values.