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Equivalence Test (TOST)/Evidence
Method evidence record

Equivalence Test (TOST)

The equivalence test using the Two One-Sided Tests (TOST) procedure is a parametric hypothesis test designed to demonstrate that the difference between two group means falls within a pre-specified equivalence region ±Δ. Introduced by Schuirmann (1987) in the context of pharmaceutical bioequivalence, TOST reverses the logic of classical null-hypothesis testing: instead of trying to detect a difference, it provides positive evidence of similarity.

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Source record

Citations copied verbatim from the method’s source record. No claim-level verification is inferred from them.

Two One-Sided Tests Procedure for Equivalence
Taxonomic method record · hypothesis-test / statistics
  • Schuirmann, D.J. (1987). A Comparison of the Two One-Sided Tests Procedure and the Power Approach for Assessing the Equivalence of Average Bioavailability. Journal of Pharmacokinetics and Biopharmaceutics, 15(6), 657–680. · DOI 10.1007/BF01068419
  • Lakens, D. (2017). Equivalence Tests: A Practical Primer for t Tests, Correlations, and Meta-Analyses. Social Psychological and Personality Science, 8(4), 355–362. · DOI 10.1177/1948550617697177
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Claims persisted in the evidence ledger, each with its own assessment.

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Related methods

Generated from the method graph and shown as machine-suggested relations — no evidence claim is inferred.

Same method familyIndependent t-testmachine-suggested · Relational suggestion, not evidence.Same method familyMann-Whitney U testmachine-suggested · Relational suggestion, not evidence.Same method familyOne-way ANOVAmachine-suggested · Relational suggestion, not evidence.Same method familyPaired t-testmachine-suggested · Relational suggestion, not evidence.Same method familyWelch t-testmachine-suggested · Relational suggestion, not evidence.

Evidence status

Sources recorded, not reviewed

Bibliographic sources are present. Claim-level evidence review has not been performed.

Sources

2 recorded citations, copied from the method source record.

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