Process / pipelineClinical / epidemiology
Risk-adjusted dose-response analysis
Risk-adjusted dose-response analysis quantifies the relationship between increasing levels of an exposure (dose) and the probability or magnitude of an outcome (response), while simultaneously controlling for baseline risk factors that could confound or modify this relationship. The method is widely applied in clinical epidemiology, pharmacoepidemiology, and environmental health research to isolate the causal contribution of exposure intensity from background risk heterogeneity among participants.
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Sources
- Greenland, S. (1995). Dose-response and trend analysis in epidemiology: alternatives to categorical analysis. Epidemiology, 6(4), 356-365. DOI: 10.1097/00001648-199507000-00005 ↗
- Rothman, K. J., Greenland, S., & Lash, T. L. (2008). Modern Epidemiology (3rd ed.). Lippincott Williams & Wilkins. ISBN: 978-0781755641