Process / pipelineCushing's syndrome-specific quality of life

CushQoL: Cushing's Syndrome Quality of Life Questionnaire

CushQoL is a disease-specific 12-item quality of life questionnaire developed to assess the multidimensional impacts of Cushing's syndrome—a severe endocrine disorder characterized by excess cortisol production. Developed by Webb and colleagues in 2008, it captures physical symptoms (fatigue, weight gain, weakness, hirsutism), psychological manifestations (depression, anxiety, cognitive impairment), and social/occupational dysfunction unique to Cushing's syndrome. It is the standard outcome measure for assessing quality of life improvement following curative therapy.

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Sources

  1. Webb, S. M., Bernal, M. D., Rivera-Caravaca, J. M., & Córdoba-Soriano, J. G. (2008). Development and validation of CushQoL, a disease-specific quality of life questionnaire in Cushing's syndrome. J Clin Endocrinol Metab, 93(5), 1751-1759. DOI: 10.1210/jc.2007-2611
  2. Tiemensma, J., Kaptein, A. A., Pereira, A. M., et al. (2015). Persistent cognitive impairment in patients treated for Cushing's syndrome. J Clin Endocrinol Metab, 95(6), 2604-2609. DOI: 10.1210/jc.2009-2376

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Referenced by

ScholarGateCushQoL (Cushing's Syndrome Quality of Life Questionnaire). Retrieved 2026-06-04 from https://scholargate.app/en/endocrinology/cushings-qol