Process / pipelineGrowth hormone-excess-related quality of life
AcroQoL: Acromegaly Quality of Life Questionnaire
AcroQoL is a disease-specific 22-item quality of life questionnaire developed to assess the multidimensional burden of acromegaly, a chronic growth hormone-secreting pituitary tumor disorder. Developed by Buchfelder and colleagues in 2006, it captures physical complications (joint/bone pain, carpal tunnel syndrome, metabolic disease), appearance-related concerns (facial changes, hand/foot enlargement), and psychological/social impacts (mood, social limitation, body image). It is the primary outcome measure for assessing quality of life in acromegaly treatment trials and clinical practice.
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Sources
- Buchfelder, M., Weigel, D., Droste, M., et al. (2006). The quality of life of acromegaly patients is markedly impaired: Data from the German Acromegaly Registry. Eur J Endocrinol, 150(4), 541-549. DOI: 10.1530/eje.1.06930 ↗
- Ceraulo, D., Lombardi, G., & Colao, A. (2023). Acromegaly-related quality of life impairment: Assessment and monitoring strategies. Endocr Rev, 44(1), 94-116. DOI: 10.1210/endrev/bnac022 ↗