Process / pipelineEcotoxicology
Bioaccumulation Model
Bioaccumulation models predict how chemical contaminants accumulate in organisms from environmental exposure (water, food, sediment). Developed by Gobas and colleagues (2006), these models quantify the kinetics of chemical uptake, metabolism, and clearance. Bioaccumulation factors (BAF) and bioconcentration factors (BCF) measure the ratio of chemical concentration in organisms to concentration in the environment. Understanding bioaccumulation is critical for assessing ecological risk from persistent organic pollutants (POPs), heavy metals, and other contaminants.
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Sources
- Arnot, J. A., & Gobas, F. A. (2006). A review of bioaccumulation factor (BAF) and bioconcentration factor (BCF) assessments for organic chemicals in aquatic organisms. Environmental Reviews, 14(4), 257-297. DOI: 10.1139/a06-012 ↗
- Clark, K. E., Gobas, F. A., & Mackay, D. (1990). Model of organic chemical uptake and clearance by fish from food and water. Environmental Science & Technology, 24(7), 1203-1213. DOI: 10.1021/es00077a022 ↗
- Meador, J. P., Stein, J. E., Hom, T., & Varanasi, U. (2006). Bioaccumulation of polycyclic aromatic hydrocarbons by marine organisms. Reviews of Environmental Contamination and Toxicology, 143, 79-165. DOI: 10.1007/978-1-4612-0731-8_3 ↗