Survival analysis
基于陆标的条件生存与动态预测分析
陆标分析(Landmark analysis)由 Anderson, Cain 和 Gelber 于 1983 年提出,用于估计在预先设定的时间点——即陆标时间(landmark)——仍然处于风险中的受试者的条件生存概率,而不是从研究开始时的生存概率。该方法是专门为避免“不朽时间偏倚”(immortal time bias)而开发的,当受试者根据某个事件(如治疗改变或生物标志物结果)进行分组时,该偏倚就会出现,而该事件只有在受试者存活足够长的时间以经历该事件后才能发生。
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来源
- Anderson, J. R., Cain, K. C. & Gelber, R. D. (1983). Analysis of Survival by Tumor Response. Journal of Clinical Oncology, 1(11), 710–719. DOI: 10.1200/JCO.1983.1.11.710 ↗
- van Houwelingen, H. C. (2007). Dynamic Prediction by Landmarking in Event History Analysis. Scandinavian Journal of Statistics, 34(1), 70–85. DOI: 10.1111/j.1467-9469.2006.00529.x ↗
如何引用本页
ScholarGate. (2026, June 1). Landmark Analysis for Conditional Survival and Dynamic Prediction. ScholarGate. https://scholargate.app/zh/survival/landmark-analysis
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