方法证据记录
Adaptive Experiment
An adaptive experiment is an experimental design in which pre-specified rules allow the protocol to be modified — such as reallocating participants to better-performing arms, stopping early for efficacy or futility, or changing sample size — based on accumulating interim data, while maintaining statistical validity. Adaptive designs are widely used in clinical trials, behavioural economics, and online platform testing to improve efficiency and ethics without sacrificing inferential rigour.
源记录
引文逐字复制自方法源记录。这些引文不代表任何层级的验证。
Adaptive Experimental Design
分类方法记录 · process-pipeline / experimental-design
- Chow, S. C., & Chang, M. (2008). Adaptive Design Methods in Clinical Trials. Chapman and Hall/CRC. · ISBN 978-1584886761
- U.S. Food and Drug Administration. (2019). Adaptive Designs for Clinical Trials of Drugs and Biologics: Guidance for Industry. FDA. · URL
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