方法证据记录
Adaptive Cohort Study
An adaptive cohort study is a longitudinal observational design that follows a defined group of individuals over time to assess exposure-outcome relationships, while incorporating pre-specified adaptation rules that allow protocol modifications — such as sample-size re-estimation, subgroup enrichment, or measurement schedule adjustments — based on accumulating interim data. Adaptations are made without compromising validity, guided by a statistical analysis plan agreed upon before data collection begins.
源记录
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Adaptive Cohort Study Design
分类方法记录 · process-pipeline / epidemiology
- VanderWeele, T. J., & Hernan, M. A. (2012). Results on differential and dependent measurement error of the exposure and the outcome using signed directed acyclic graphs. American Journal of Epidemiology, 175(12), 1303–1310. · DOI 10.1093/aje/kwr458
- Cohort study. Wikipedia. · URL
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