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自适应竞争风险分析

自适应竞争风险分析将Fine-Gray亚分布风险模型——该模型在存在其他互斥的失效原因时,对某一失效原因的累积发生率进行建模——与自适应或分组序贯中期监测规则相结合。这允许临床试验或观察性研究根据累积的竞争风险数据在过程中进行修改(例如,样本量重新评估、提前终止),同时保持预先设定的I类错误控制。

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自适应竞争风险分析
自适应试验设计生存分析

来源

  1. Fine, J. P., & Gray, R. J. (1999). A proportional hazards model for the subdistribution of a competing risk. Journal of the American Statistical Association, 94(446), 496–509. DOI: 10.1080/01621459.1999.10474144
  2. Beyersmann, J., Allignol, A., & Schumacher, M. (2012). Competing Risks and Multistate Models with R. Springer. ISBN: 978-1461420767

如何引用本页

ScholarGate. (2026, June 3). Adaptive Competing Risks Analysis. ScholarGate. https://scholargate.app/zh/epidemiology/adaptive-competing-risks-analysis

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ScholarGateAdaptive Competing Risks Analysis (Adaptive Competing Risks Analysis). 于 2026-06-15 检索自 https://scholargate.app/zh/epidemiology/adaptive-competing-risks-analysis · 数据集: https://doi.org/10.5281/zenodo.20539026