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基于体素的形态学分析×结构方程模型×
领域神经影像研究统计学
方法族Process / pipelineProcess / pipeline
起源年份20001921
提出者John AshburnerSewall Wright
类型Structural MRI gray matter analysis pipelineMethod
开创性文献Ashburner, J., & Friston, K. J. (2000). Voxel-based morphometry—the methods. NeuroImage, 11(6), 805–821. DOI ↗Jöreskog, K. G., & Sörbom, D. (1973). LISREL: A general computer program for estimating a linear structural equation system. Research Bulletin 73-5. University of Stockholm. link ↗
别名VBM, grey matter morphometrySEM, path analysis, latent variable modeling, causal modeling
相关23
摘要Voxel-Based Morphometry (VBM) is a whole-brain statistical technique for detecting local differences in gray matter volume or concentration from structural MRI. Introduced by John Ashburner and Karl Friston in 2000, VBM enables researchers to identify regional brain volume changes associated with disease, aging, learning, and other factors without requiring a priori region-of-interest definitions.Structural equation modeling (SEM) is a comprehensive statistical framework combining path analysis (Sewall Wright, 1921) and confirmatory factor analysis to test complex causal models linking observed and latent variables. Formalized by Jöreskog (1973) with LISREL software, SEM enables simultaneous estimation of measurement relationships (how variables measure latent constructs) and structural relationships (how constructs influence outcomes), making it powerful for theory testing in psychology, epidemiology, organizational research, and health sciences where complex mediation, moderation, and latent processes require integrated analysis.
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ScholarGate方法对比: Voxel-Based Morphometry · Structural Equation Modeling. 于 2026-06-15 检索自 https://scholargate.app/zh/compare