方法对比
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| 风险调整生存分析× | Cox比例风险模型× | |
|---|---|---|
| 领域 | 流行病学 | 流行病学 |
| 方法族 | Process / pipeline | Process / pipeline |
| 起源年份≠ | 1972 (Cox regression); broader covariate-adjusted survival methods developed 1970s–1990s | 1972 |
| 提出者≠ | D. R. Cox (regression framework); extensions via Kaplan & Meier, Breslow, and others | Sir David Roxbee Cox |
| 类型≠ | Observational and experimental analytical method | Semi-parametric regression model |
| 开创性文献≠ | Cox, D. R. (1972). Regression models and life-tables. Journal of the Royal Statistical Society, Series B, 34(2), 187–220. link ↗ | Cox, D. R. (1972). Regression models and life-tables. Journal of the Royal Statistical Society: Series B (Methodological), 34(2), 187–202. DOI ↗ |
| 别名 | covariate-adjusted survival analysis, adjusted time-to-event analysis, risk-stratified survival analysis, adjusted Kaplan-Meier / Cox analysis | Cox regression, Cox PH model, proportional hazards model, CPH |
| 相关 | 5 | 5 |
| 摘要≠ | Risk-adjusted survival analysis estimates the time to an event of interest — such as death, relapse, or hospital readmission — while simultaneously accounting for baseline differences in patient characteristics (covariates). By incorporating confounders such as age, comorbidities, or disease severity, it produces hazard ratios, survival curves, and median survival estimates that are attributable to the factor of interest rather than to pre-existing risk differences between groups. | The Cox proportional hazards model is a semi-parametric regression method that estimates the effect of one or more covariates on the hazard — the instantaneous rate of an event such as death, relapse, or failure — while making no assumption about the shape of the baseline hazard function. Introduced by David Cox in 1972, it is the dominant tool for multivariable survival analysis in clinical and epidemiological research. |
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