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回顾性生存分析×Cox比例风险模型×
领域流行病学流行病学
方法族Process / pipelineProcess / pipeline
起源年份1970s–1980s (retrospective variant established)1972
提出者Kaplan & Meier (foundational estimator, 1958); Cox (regression model, 1972); retrospective application is a design variant documented since the 1970sSir David Roxbee Cox
类型Retrospective observational analytical studySemi-parametric regression model
开创性文献Collett, D. (2015). Modelling Survival Data in Medical Research (3rd ed.). CRC Press. ISBN: 978-1439856789Cox, D. R. (1972). Regression models and life-tables. Journal of the Royal Statistical Society: Series B (Methodological), 34(2), 187–202. DOI ↗
别名historical survival study, retrospective time-to-event analysis, retrospective follow-up survival study, archival survival analysisCox regression, Cox PH model, proportional hazards model, CPH
相关55
摘要Retrospective survival analysis applies time-to-event statistical methods — most commonly the Kaplan-Meier estimator and Cox proportional hazards regression — to data collected from past records rather than through prospective follow-up. The researcher looks back at medical records, disease registries, or administrative databases to reconstruct each patient's journey from a defined starting point (e.g., diagnosis or surgery) to an outcome of interest (e.g., death, relapse, or hospital readmission), making it a cost-efficient approach for studying prognosis and risk factors when prospective follow-up is not feasible.The Cox proportional hazards model is a semi-parametric regression method that estimates the effect of one or more covariates on the hazard — the instantaneous rate of an event such as death, relapse, or failure — while making no assumption about the shape of the baseline hazard function. Introduced by David Cox in 1972, it is the dominant tool for multivariable survival analysis in clinical and epidemiological research.
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ScholarGate方法对比: Retrospective survival analysis · Cox proportional hazards. 于 2026-06-20 检索自 https://scholargate.app/zh/compare