方法对比
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| 生存研究的功效分析× | 对生存曲线进行比较的 Log-Rank 检验× | |
|---|---|---|
| 领域≠ | 统计学 | 生存分析 |
| 方法族≠ | Hypothesis test | Survival analysis |
| 起源年份≠ | 1981 | 1966 |
| 提出者≠ | — | Mantel, N. |
| 类型≠ | Sample size determination for survival outcomes | Non-parametric hypothesis test |
| 开创性文献≠ | Schoenfeld, D. A. (1981). The asymptotic properties of nonparametric tests for comparing survival distributions. Biometrika, 68(1), 316–319. DOI ↗ | Mantel, N. (1966). Evaluation of Survival Data and Two New Rank Order Statistics Arising in Its Consideration. Cancer Chemotherapy Reports, 50(3), 163–170. link ↗ |
| 别名 | log-rank power analysis, cox regression power analysis, survival power analysis, Sağkalım Analizi Güç Analizi | Mantel log-rank test, Mantel-Cox test, log-rank sağkalım testi, Log-Rank Testi |
| 相关≠ | 6 | 2 |
| 摘要≠ | Power analysis for survival studies determines how many participants — and how many observed events — are required so that a log-rank test or Cox regression has a sufficient probability of detecting a clinically meaningful difference in survival between groups. The foundational formulas were derived by Schoenfeld (1981) and Lachin (1981) and remain the standard approach in clinical trial planning. | The log-rank test, developed by Nathan Mantel in 1966, is a non-parametric hypothesis test that compares the overall survival experience of two or more groups throughout the entire follow-up period. It is the standard companion to Kaplan-Meier curves and determines whether observed differences between curves are statistically meaningful. |
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