方法对比

	Plackett-Burman 筛选设计	响应面方法 (RSM)
领域	实验设计	实验设计
方法族	Hypothesis test	Hypothesis test
起源年份	1946	1951
提出者	R.L. Plackett & J.P. Burman	George E. P. Box & K. B. Wilson
类型	Two-level orthogonal array	Second-order polynomial response surface model
开创性文献	Plackett, R.L. & Burman, J.P. (1946). The Design of Optimum Multifactorial Experiments. Biometrika, 33(4), 305–325.	Box, G. E. P. & Wilson, K. B. (1951). On the experimental attainment of optimum conditions. Journal of the Royal Statistical Society, Series B, 13(1), 1–45.
别名	PB design, PB screening, Plackett-Burman Tarama Deseni	RSM, Central Composite Design, Box-Behnken Design, CCD
相关	4	7
摘要	The Plackett-Burman design is a two-level orthogonal screening design introduced by R.L. Plackett and J.P. Burman in 1946 that allows researchers to estimate the main effect of each factor independently using the smallest possible number of experimental runs. Run counts are always multiples of four, making it exceptionally economical for studies with many candidate factors.	Response Surface Methodology is a collection of statistical and mathematical techniques for building an empirical second-order polynomial model that relates a continuous response variable to two or more controllable input factors, and then locating the factor settings that optimize that response. The approach was introduced by George E. P. Box and K. B. Wilson in their landmark 1951 paper and has since become a cornerstone of process optimization across engineering, chemistry, food science, and pharmaceutics.