方法对比

	试点全因子实验	响应面方法 (RSM)
领域	实验设计	实验设计
方法族	Process / pipeline	Hypothesis test
起源年份	1920s (Fisher); pilot usage formalised mid-20th century	1951
提出者	R. A. Fisher (full factorial foundations); pilot application codified in applied DOE literature (Box, Hunter & Hunter; Montgomery)	George E. P. Box & K. B. Wilson
类型	Experimental design (pilot/screening phase)	Second-order polynomial response surface model
开创性文献	Montgomery, D. C. (2017). Design and Analysis of Experiments (9th ed.). Wiley. ISBN: 978-1119113478	Box, G. E. P. & Wilson, K. B. (1951). On the experimental attainment of optimum conditions. Journal of the Royal Statistical Society, Series B, 13(1), 1–45.
别名	pilot factorial design, pilot 2^k design, pilot complete factorial experiment, screening factorial pilot	RSM, Central Composite Design, Box-Behnken Design, CCD
相关	3	7
摘要	A pilot full factorial experiment is a small-scale, complete crossing of all selected factors at all their levels, run before a definitive study to gather preliminary effect estimates, assess variability, and verify experimental logistics. It retains the complete combinatorial structure of a full factorial design — every combination of factor levels is tested — but is intentionally limited in scope (fewer replicates, narrower factor ranges) to conserve resources while maximising learning about factor effects and interactions before committing to a larger investigation.	Response Surface Methodology is a collection of statistical and mathematical techniques for building an empirical second-order polynomial model that relates a continuous response variable to two or more controllable input factors, and then locating the factor settings that optimize that response. The approach was introduced by George E. P. Box and K. B. Wilson in their landmark 1951 paper and has since become a cornerstone of process optimization across engineering, chemistry, food science, and pharmaceutics.