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优化辅助 Box-Behnken 设计×优化辅助的中心复合设计×
领域实验设计实验设计
方法族Process / pipelineProcess / pipeline
起源年份1960 (BBD); optimization integration established 1980s–1990s1951 (CCD); optimization coupling formalized 1970s–1990s
提出者Box & Behnken (design); Derringer & Suich (desirability optimization)Box & Wilson (CCD, 1951); optimization integration by Myers, Montgomery & colleagues
类型Experimental design with post-modeling optimizationExperimental design with mathematical optimization
开创性文献Box, G. E. P., & Behnken, D. W. (1960). Some new three level designs for the study of quantitative variables. Technometrics, 2(4), 455–475. DOI ↗Myers, R. H., Montgomery, D. C., & Anderson-Cook, C. M. (2009). Response Surface Methodology: Process and Product Optimization Using Designed Experiments (3rd ed.). Wiley. ISBN: 978-0470174463
别名BBD with optimization, Box-Behnken design optimization, RSM-BBD optimization, Box-Behnken response optimizationCCD with optimization, optimized CCD, RSM-CCD optimization, central composite design with response optimization
相关53
摘要Optimization-assisted Box-Behnken design (BBD) combines the Box-Behnken three-level experimental design with a formal optimization step to locate factor settings that maximize, minimize, or hit a target for one or more responses. BBD fits a second-order response surface model using fewer runs than a full factorial, and the optimization stage — typically via desirability functions or numerical search — then exploits that fitted model to identify the true optimum within the experimental region.Optimization-assisted central composite design (CCD) combines the rotatable, second-order experimental layout of central composite design with mathematical optimization algorithms — typically desirability functions, response surface optimization, or metaheuristics — to find the factor settings that simultaneously maximize, minimize, or hit target values for one or more response variables. It is the most widely applied response-surface optimization workflow in chemical, pharmaceutical, food science, and manufacturing engineering.
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ScholarGate方法对比: Optimization-assisted Box-Behnken design · Optimization-assisted central composite design. 于 2026-06-18 检索自 https://scholargate.app/zh/compare