方法对比

	荟萃分析诊断准确性研究	筛查试验评估
领域	流行病学	流行病学
方法族	Process / pipeline	Process / pipeline
起源年份	1993–2005 (foundational models)	1968 (Wilson-Jungner principles); statistical framework developed 1970s–2000s
提出者	Moses, Shapiro & Littenberg (SROC framework, 1993); Reitsma et al. (bivariate model, 2005)	Wilson & Jungner (WHO criteria, 1968); foundational work by Pepe, Altman, and others in statistical test evaluation
类型	Quantitative systematic synthesis	Observational diagnostic / epidemiological evaluation design
开创性文献	Reitsma, J. B., Glas, A. S., Rutjes, A. W., Scholten, R. J., Bossuyt, P. M., & Zwinderman, A. H. (2005). Bivariate analysis of sensitivity and specificity produces informative summary measures in diagnostic reviews. Journal of Clinical Epidemiology, 58(10), 982–990.	Wilson, J. M. G., & Jungner, G. (1968). Principles and Practice of Screening for Disease. World Health Organization. Public Health Papers No. 34.
别名	DTA meta-analysis, diagnostic meta-analysis, systematic review of diagnostic accuracy, pooled diagnostic accuracy	screening study, screening performance evaluation, screening accuracy assessment, STE
相关	2	6
摘要	A meta-analytic diagnostic accuracy study systematically identifies and pools sensitivity and specificity data from multiple primary diagnostic test accuracy studies. Using the bivariate or hierarchical summary ROC (HSROC) model, it produces a joint summary of a test's ability to correctly classify diseased and non-diseased individuals across diverse clinical settings, accounting for the inherent trade-off between sensitivity and specificity.	Screening test evaluation is a systematic epidemiological approach for assessing whether a test or program can accurately and cost-effectively identify individuals with a condition before symptoms appear. It quantifies diagnostic performance metrics — sensitivity, specificity, predictive values, and the ROC curve — and evaluates whether a screening program meets established public health criteria for adoption and harm-benefit balance.