方法对比
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| 匹配的Kaplan-Meier分析× | Cox比例风险模型× | |
|---|---|---|
| 领域 | 流行病学 | 流行病学 |
| 方法族 | Process / pipeline | Process / pipeline |
| 起源年份≠ | 1958 (KM); matched application formalized 1980s–2000s | 1972 |
| 提出者≠ | Kaplan & Meier (KM method, 1958); matching extensions developed through propensity score methods (Rosenbaum & Rubin, 1983) | Sir David Roxbee Cox |
| 类型≠ | Nonparametric survival analysis with observational confounder control | Semi-parametric regression model |
| 开创性文献≠ | Kaplan, E. L., & Meier, P. (1958). Nonparametric estimation from incomplete observations. Journal of the American Statistical Association, 53(282), 457-481. DOI ↗ | Cox, D. R. (1972). Regression models and life-tables. Journal of the Royal Statistical Society: Series B (Methodological), 34(2), 187–202. DOI ↗ |
| 别名 | KM analysis in matched cohorts, propensity-matched survival curves, matched survival analysis, paired Kaplan-Meier | Cox regression, Cox PH model, proportional hazards model, CPH |
| 相关≠ | 6 | 5 |
| 摘要≠ | Matched Kaplan-Meier analysis estimates and compares survival functions in groups that have been pre-balanced through individual or propensity-score matching. By applying the Kaplan-Meier product-limit estimator to matched cohorts or matched pairs, investigators can visualize time-to-event outcomes while controlling for confounders that would otherwise distort treatment or exposure comparisons in observational data. | The Cox proportional hazards model is a semi-parametric regression method that estimates the effect of one or more covariates on the hazard — the instantaneous rate of an event such as death, relapse, or failure — while making no assumption about the shape of the baseline hazard function. Introduced by David Cox in 1972, it is the dominant tool for multivariable survival analysis in clinical and epidemiological research. |
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