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领域流行病学研究统计学
方法族Process / pipelineProcess / pipeline
起源年份1950s–1970s1983
提出者Brian MacMahon and others; systematised by Schlesselman (1982)Paul Rosenbaum and Donald Rubin
类型Observational analytic designMethod
开创性文献Rothman, K. J., Greenland, S., & Lash, T. L. (2008). Modern Epidemiology (3rd ed.). Lippincott Williams & Wilkins. ISBN: 978-0781755474Rosenbaum, P. R., & Rubin, D. B. (1983). The central role of the propensity score in observational studies for causal effects. Biometrika, 70(1), 41–55. DOI ↗
别名matched case-referent study, individually matched case-control, pair-matched case-control, matched case-control designPSM, propensity score weighting, covariate balance
相关53
摘要A matched case-control study is an observational epidemiological design in which each case (a person with the disease or outcome of interest) is paired with one or more controls (persons without the outcome) who share one or more characteristics — such as age, sex, or clinical setting — to control confounding. Exposure history is then compared between cases and their matched controls to estimate the odds ratio of the exposure-disease association.Propensity score matching (PSM) is a method for reducing confounding bias in observational studies by balancing baseline characteristics between treatment groups, simulating randomization. Developed by Rosenbaum and Rubin (1983), it estimates the probability of receiving treatment given observed covariates, then matches or weights treated and control individuals with similar treatment probabilities. Widely used in medicine, epidemiology, and policy evaluation when randomized trials are infeasible or unethical, enabling estimation of treatment effects while controlling for selection bias.
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ScholarGate方法对比: Matched case-control study · Propensity Score Matching. 于 2026-06-17 检索自 https://scholargate.app/zh/compare